Prof Ian Wilcox



Prof Ian Wilcox

Prof Ian Wilcox

  • Cardiologist, Royal Prince Alfred Hospital (Senior VMO)
  • Clinical Professor, Sydney Medical School, University of Sydney
  • Cardiologist, Strathfield Private Hospital
  • Consultant Cardiologist, Chris O'Brien Lifehouse

Professor Ian Wilcox was born in Melbourne and undertook medical training in Newcastle on Tyne (UK), including a BMedSci with First Class Honours in Immunology. His postgraduate education and training in Cardiology was at Sydney University and Royal Prince Alfred Hospital.

Professor Wilcox’s clinical research career includes a PhD on Predicting Risk in Unstable Angina funded by a National Heart Foundation Scholarship. His postdoctoral research on the Cardiovascular Consequences of Obstructive Sleep Apnoea was funded by the National Health and Medical Research Council in collaboration with Professor Colin Sullivan.

He has supervised 8 PhD and Masters Students. Current research interests include the role of sleep apnoea in cardiac arrhythmias, congestive heart failure, large vessel vascular disease and atherosclerosis. He has over 40 publications in major journals and 1200 citations in the medical literature.

In addition he has a major interest in innovation in clinical research and practice in cardiology including new methods to detect heart failure decompensation.

Professor Wilcox jointly established the Cardiac Surgery Program at Strathfield Private Hospital in 1991 and founded Central Sydney Cardiology, an academic private practice, in 1999.


Prof. Wilcox’s waiting list for new POTS patients is at capacity and we are therefore unable to accommodate new referrals in a timely manner.

As such, he (and our other Doctors in the Practice) will not be taking on any new POTS cases.

We will give an update if this changes in the future.

  • Complex adult heart disease including coronary, valvular and myocardial disease, cardiac arrhythmias and inherited heart disease.
  • Cardiac imaging including stress echocardiography and 3D echocardiography.
  • Heart-lung interactions including the cardiovascular consequences of sleep apnoea.

Selected Publications:

Metabolite signatures of heart failure, sleep apnoea, their interaction, and outcomes in the community. Shashwati Dutta*, Desmond Li*, Andy Wang, Mark Ishak, Kristina Cook, Melissa Farnham, Hasthi Dissanayake, Peter Cistulli, Imre Hunyor, Renping Liu, Ian Wilcox, Yen Chin Koay, Jean Yang, Sean Lal, John F. O’Sullivan. ESC Heart Failure (accepted 12/09/2021)

A Leadless Intracardiac Transcatheter Pacing System. Chan KH, McGrady M, Wilcox IN Engl J Med. 2016 Jun 30;374(26):2604. doi: 10.1056/NEJMc1604852#SA1.

Wilcox I, Chan KH, Dimitri H. Diagnosis and treatment of obstructive sleep apnea is key to achieving optimal results after catheter ablation of atrial fibrillation. J Am Coll Cardiol. 2014;63(6):607-8.

Fulcher J, Wilcox I. Basal stress cardiomyopathy induced by exogenous catecholamines in younger adults. Int J Cardiol. 2013;168(6):158-60.

Arnott C, Wilcox I, Patel S.  A Case of ST Elevation Myocardial Infarction Secondary to Heparin-induced Thrombocytopaenia with Thrombosis. Heart Lung Circ. 2012 Dec;21(12):841-3

Wilcox I, Chan KH, Lattimore JD. Hypoxia and inflammation. N Engl J Med. 2011;364(20):1976-7

Chan KH, Wilcox I. Obstructive Sleep Apnea: a Novel Trigger for Cardiac Arrhythmias and Potential Therapeutic Target. Expert Review of Cardiovascular Therapy 20108(7):981-94

Wilcox I, Semsarian C. Obstructive sleep apnea: a respiratory syndrome with protean cardiovascular manifestations. (Editorial) Journal of the American College of Cardiology 2009;54:1810-11

Lattimore JD, Wilcox I, Adams MR, Kilian JG, Celermajer DS. Treatment of obstructive sleep apnoea leads to enhanced pulmonary vascular nitric oxide release. Int J Cardiol. 2008;126(2):229-33.

Lattimore J.D., Wilcox I, Skilton M, Langenfeld M, Celermajer DS. Treatment of obstructive sleep apnoea leads to improved microvascular endothelial function in the systemic circulation. Thorax.  2006 Jun;61(6):491-5. Epub 2006 Mar 14

Wilcox I, Booth V, Lattimore JD. Sleep apnea and heart disease. N Engl J Med. 2006 ; 354(10):1086-9

Lattimore J-D, Celermajer D.S, Wilcox I. Sleep Apnea and Cardiovascular Disease. Journal of the American College of Cardiology 2003;41:1429-37

Wilcox I, McNamara SG, Sullivan CE. Central sleep apnea and heart failure. N Engl J Med 2000;342:293

Wilcox I, McNamara  SG, Collins FL, Grunstein RR, Sullivan CE ‘Syndrome Z’:  The Interaction of Sleep Apnoea, Vascular Risk Factors and Heart Disease. Thorax 1998;53 (suppl 3) S12:S25-28

Wilcox I, McNamara SG, Dodd MJ, Sullivan CE. Ventilatory control in patients with sleep apnoea and left ventricular dysfunction: comparison of obstructive and central sleep apnoea. European Respiratory Journal 1998;11:7-13 [Editorial: Augmented chemosensitivity to hypercapnia: another link in our understanding of the pathogenesis of Cheyne-Stokes respiration. Hanly P. pp3-4]

Wilcox I, Grunstein RR., Hedner JA., Doyle J, Collins FL, Fletcher PJ, Kelly DT, Sullivan CE. Effect of nasal continuous positive airway pressure during sleep on 24-hour blood pressure in obstructive sleep apnea. Sleep 1993;16:539-45

Wilcox I, Grunstein RR, Collins FL, Doyle J, Kelly DT, Sullivan CE. Circadian variation in blood pressure in obstructive sleep apnea. Blood Pressure 1992;1:219-222

Wilcox I, Freedman SB, Allman KC, Collins FL, Leitch JW, Kelly DT, Harris PJ. The prognostic significance of a pre-discharge exercise test in risk stratification after unstable angina pectoris. Journal of theAmericanCollege of Cardiology 1991;18:677-83 [Editorial: Vagaries of predischarge exercise stress testing in acute myocardial ischemic syndromes. Ferlinz J. pp 684-6]

Wilcox I, Freedman SB, McCredie RJ, Carter GS, Kelly DT, Harris PJ. Risk of adverse outcome in patients admitted to the coronary care unit with suspected unstable angina. American Journal of Cardiology 1989;64:845‑848